Knowledge

If you've searched this, you've probably already met the hype. NMN gets talked about as the supplement that "reverses ageing," "restores your energy," or "turns back your cellular clock." And some part of you — the sensible part — is asking the obvious question: is any of that real, or am I about to spend £40 a month on nothing? That's exactly the right question, and you deserve a straight answer rather than a sales pitch. We make NMN, so we're not neutral, and we'll say so plainly. But we'd genuinely rather you understood the evidence and bought nothing than bought from us on a promise we can't keep. So here is the honest version. First, what does "work" even mean here? This is where most of the confusion lives, because "does NMN work?" is really two different questions stacked on top of each other: Does NMN raise NAD+ levels in the body? Does raising NAD+ lead to outcomes you'd actually notice or care about? These have very different answers, and people who want to sell you something tend to answer the first question and then quietly act as if they've answered the second. We won't do that. Let's take them one at a time. If you're new to the NAD+ piece, our plain-English explainer on what NAD+ is is the place to start — everything below assumes that groundwork. Question 1: Does NMN raise NAD+? This is the part with the most supportive evidence. NAD+ is a coenzyme every cell uses, and its levels tend to fall as we age — that decline is one of the more consistent findings in the field. NMN is a precursor: a building block the body converts into NAD+ through its own pathways. Several human trials have looked at whether taking NMN raises NAD+ markers in the blood, and the results have been broadly encouraging — multiple studies have reported measurable increases. So on the narrow, mechanical question of "does swallowing NMN move the NAD+ number," the early human evidence leans yes. That sounds promising, and it is — but notice how specific it is. "A marker in the blood went up in a study" is a real finding. It is not the same as "you will feel different" or "you will age more slowly." Which brings us to the harder question. Question 2: Does that actually do anything you'd notice? Here we have to be honest in a way most marketing isn't: this is still an open question. Most of the dramatic claims you've seen — more energy, better sleep, slower ageing, sharper focus — come from one of three places: animal studies (often in mice, given doses that don't map neatly onto humans), early small-scale human trials, or, frankly, marketing departments running ahead of both. The large, long-term human trials that would tell us what NMN does for healthy people over years simply haven't been completed yet. Independent science journalists have made the same point repeatedly: the marketing around NAD+ supplements has moved well ahead of the evidence. So if someone promises you NMN will give you energy, fix your sleep, or reverse your ageing, they are describing a hope, not a result. Under UK advertising rules we're not even allowed to make those claims — and the honest truth is we wouldn't, because the evidence doesn't support them. So why would anyone take it? A fair question, and the honest answer is: people take NMN for different reasons, and only you can decide if yours is a good one. Some people take it because the underlying logic is sound and the mechanism is plausible — NAD+ matters, it declines with age, NMN can raise it — and they're comfortable acting on a reasonable hypothesis while the long-term research catches up. Others would rather wait until there's more certainty, and that is an entirely defensible position too. There's no shame in deciding the evidence isn't there yet for you. What we'd gently push back on is taking NMN expecting to feel something. Most people don't feel anything day to day, and that's normal — NAD+ metabolism isn't a stimulant. If your test of "does it work" is whether you feel a buzz, you'll likely conclude it doesn't, because that was never what it was doing. How to decide if it's worth it for you Rather than tell you what to do, here's the framework we'd use if we were the customer: Have you got the basics handled first? Sleep, movement, and a reasonable diet do more for how you age than any capsule, and the research community broadly agrees. NMN is a "once the foundations are in place" consideration, not a shortcut around them. Are you comfortable acting on early evidence? If you need settled, long-term proof before spending money, NMN isn't there yet, and that's a perfectly sensible reason to wait. Can you afford it without resentment? At a real monthly cost, NMN should be something you're relaxed about spending on, not something you'll feel cheated by if the big trials eventually come back lukewarm. Are you buying from a brand that's honest about all of this? If a label promises to reverse ageing or boost your energy, that tells you more about the brand than the molecule. Walk away from anyone selling certainty. If you do try it, here's what actually matters Assuming you've decided it's worth a go, the things that genuinely affect what you get are unglamorous and practical: The form and purity — what the raw material actually is, and whether it's third-party tested. Our NMN uses Uthever® and is tested per batch; you should expect that level of transparency from anyone. The dose — whether it matches what's been studied. We cover this honestly in our NMN dose guide. Consistency — NMN is a daily-routine supplement, not a one-off. Whatever it's doing, it's doing it quietly and over time. Your expectations — set them at the level the evidence supports, which is "a reasonable bet on a well-studied molecule," not "a transformation." The honest bottom line Does NMN work? On the narrow question — does it raise NAD+ in humans — the early evidence leans yes. On the question most people actually mean — will it noticeably change my health or how I age — the honest answer is we don't know yet, and anyone who tells you otherwise is ahead of the evidence. That's not the answer a hype-driven brand would give. But it's the true one, and if you're the kind of person who searched "does NMN actually work" instead of "buy NMN now," it's probably the answer you wanted. If you'd like the fuller, label-by-label version — including the exact questions worth asking any NMN brand, us included — our free NMN Buyer's Guide lays it out without the hype. Frequently asked questions Does NMN really work?On the narrow question of whether NMN raises NAD+ levels in humans, several early trials have reported measurable increases, so the mechanism has supportive evidence. Whether that translates into noticeable health effects is still being studied and should not be treated as settled. Will I feel anything when I take NMN?Most people don't feel anything day to day, and that's normal. NMN is not a stimulant; it works at the level of cellular metabolism, not as something you'd feel like a caffeine hit. Is NMN a waste of money?That depends on your expectations. If you expect a noticeable transformation, the evidence doesn't support that yet. If you're comfortable acting on early but encouraging research about a well-studied molecule, many people consider it a reasonable choice. Get the basics — sleep, movement, diet — in place first. How long until NMN works?Because NMN isn't something you typically feel, there's no "kicks in" moment. It's a daily-routine supplement studied over weeks and months, not hours. Is NMN proven to reverse ageing?No. No supplement is proven to reverse ageing in humans. Claims like that go beyond the evidence and are not permitted under UK advertising rules. Food supplement. Not a medicine. Does not diagnose, treat, cure or prevent any disease. Food supplements should not be used as a substitute for a varied, balanced diet and a healthy lifestyle.

It's usually the second question people ask. The first is whether NMN does anything at all — we've answered that one honestly in Does NMN actually work? — and the moment someone decides it might be worth a try, the next question follows naturally: when? Thirty? Forty? Is fifty-five too late? Is twenty-eight too early? You'll find plenty of confident answers online. Most of them come from people selling NMN, and most of them — conveniently — conclude that whatever age you happen to be is exactly the right age to start. We make NMN too, so treat us with the same scepticism. But here is the honest version: there is no scientifically established "right age" to start taking NMN. Anyone who gives you a precise one is making it up. What the research can tell you is roughly how NAD+ behaves over a lifetime, and that's enough to think about the question sensibly. What actually changes with age NAD+ is a coenzyme found in every living cell. The finding that matters here is one of the more consistent ones in the field: NAD+ levels tend to decline as we age. The decline is gradual, it varies between people, and researchers are still mapping exactly when it starts and how steep it is in different tissues. What the research does not say is that this decline produces a specific problem at a specific age that a supplement then fixes. The large, long-term human trials that would connect those dots haven't been completed. So the honest framing isn't "your NAD+ falls off a cliff at 40, act now" — it's "this number drifts downward over decades, raising it with a precursor like NMN appears possible in early human studies, and what that ultimately does for health at any age is still being worked out." That uncertainty cuts both ways, and it's worth sitting with before spending money. The honest answer for each decade In your 20s and early 30s. Your natural NAD+ levels are at or near their lifetime peak. Most of the human research on NMN has been done in middle-aged and older adults, not people in their twenties — so this is the age group with the least relevant evidence and, arguably, the least reason to act on it. If you're here, the unglamorous truth is that sleep, training, and diet are doing far more for you than any precursor could, and the sensible move is probably patience: the research will be considerably more mature by the time the question becomes more relevant to you. In your 40s. This is the decade when most of our readers first take the question seriously, and it's also where a meaningful share of the human research has focused — middle-aged participants are the typical study population. The age-related NAD+ decline is no longer hypothetical for this group, which is why the interest is reasonable rather than gimmicky. Whether acting on it is worth it is a personal judgement about early evidence, cost, and expectations — we've written a fuller, demographic-specific picture in NMN for women over 40. In your 50s and 60s. Much of the human NMN research has recruited participants in this range, so if anyone can claim the evidence is "about people like me", it's this group. The same caveat applies as everywhere else: studies measuring NAD+ markers are not studies proving outcomes you'd notice.  70 and beyond. Is it "too late"? There's no evidence for a cut-off age after which NMN does nothing, and trials have included older adults. But this is also the age group where the more important sentence in this article applies most strongly: if you take regular medication or manage a health condition, talk to your GP or pharmacist before adding any supplement. That's not legal boilerplate — interactions and individual circumstances matter more with each decade. Notice what's missing from all four paragraphs: a recommendation. That's deliberate. The evidence doesn't currently support telling a 32-year-old to start now or telling a 58-year-old they've missed the window. Both claims would be inventions. A better question than "what age?" In our experience, "what age should I start?" is usually standing in for a more useful question: at my age, is this a reasonable use of money? That one you can actually answer, with the same framework we use in Does NMN actually work? Foundations first, at every age. Sleep, movement, diet, and not smoking out-perform any supplement at 30, 50, and 70 alike. The research community is unambiguous on this. NMN is a "once the basics are handled" consideration — never a substitute for them. The older you are, the more the existing research speaks to you. Most human NMN studies recruited middle-aged and older adults. A 55-year-old is reasoning from closer evidence than a 25-year-old. The younger you are, the stronger the case for waiting. Not because NMN is known to do nothing in younger people — but because the research is moving, your natural levels are higher, and the question will be better answered in five years than it is today. At any age: can you afford it without resentment? A daily supplement is a recurring cost. If the big trials eventually come back lukewarm, you should be able to shrug rather than feel cheated. If you do decide to start Whatever age you start at, the practical things that matter are the same — and they're the same ones we list everywhere, because they don't change with the buyer's birthday: The dose. Human studies have typically used daily doses in the hundreds of milligrams. The raw material and testing. A named raw material (ours is Uthever®) and per-batch third-party testing are reasonable minimum standards to hold any brand to — us included. Consistency over intensity. NMN is studied as a daily routine over weeks and months. Starting at the "perfect" age and taking it sporadically makes less sense than starting whenever you start and being consistent. Expectations set by evidence, not marketing. Most people don't feel anything day to day, at any age. That's normal, and we'd rather tell you now than have you discover it with a quiet sense of having been had. The honest bottom line There is no proven right age to start taking NMN, and you should be wary of anyone who names one. What can be said honestly: NAD+ tends to decline with age; most human NMN research has involved middle-aged and older adults; and the case for waiting is strongest when you're young and weakest as the study populations start to look like you. Beyond that, it's a personal decision about early evidence and money — one we'd rather you made clear-eyed than rushed. If you want the fuller framework — including the exact questions to ask any NMN brand before buying, us included. Frequently asked questions What is the best age to start taking NMN?There is no scientifically established "best age". NAD+ levels tend to decline gradually with age, and most human NMN research has involved middle-aged and older adults, but no study has identified an optimal starting age. Any precise answer is marketing, not science. Should I take NMN in my 20s or 30s?This is the age group with the least relevant research — most human studies recruited older participants — and natural NAD+ levels are at or near their peak. Many people in this group reasonably choose to wait while the research matures and focus on sleep, movement, and diet instead. Is 50 or 60 too late to start NMN?No evidence suggests a cut-off age. In fact, much of the human research has been conducted in people in this age range. As at any age, anyone taking medication or managing a health condition should speak to their GP or pharmacist before starting a supplement. Does NMN work differently at different ages?Researchers are still working this out. Age-related NAD+ decline is one of the more consistent findings in the field, but how raising NAD+ with a precursor plays out at different ages — and whether it produces effects you'd notice — has not been established in long-term human trials. Food supplement. Do not exceed the recommended daily dose. Food supplements should not be used as a substitute for a varied, balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, taking medication, or have a medical condition, please consult your doctor before starting.

If you've spent any time reading about NMN, you've probably seen it mentioned in the same breath as resveratrol. The two come up together so often that many people assume they're meant to be taken as a pair. So what's the actual reasoning behind the pairing — and does the research support it? Here's an honest walk through what's known, what's still theory, and how to think about it for yourself. The idea behind the pairing The pairing rests on a single biological idea about how two different molecules are thought to act on the same system. NMN is a precursor to NAD+, a coenzyme your cells use in hundreds of processes. NAD+ levels are understood to decline with age, and NMN is one of the molecules the body can convert into NAD+. Resveratrol is a polyphenol found naturally in grape skins, red wine and Japanese knotweed. In laboratory research it has been studied as a compound that interacts with a family of proteins called sirtuins. The theory that ties them together is straightforward: sirtuins are thought to depend on NAD+ to do their work. So the reasoning goes that one molecule helps supply the NAD+ and the other interacts with the proteins that use it. That's the mechanism people are describing when they call it a "stack." It's worth being precise about the status of this idea. Much of it comes from cell and animal research, and the way these molecules behave in a dish or in a mouse does not automatically translate to the same effect in a person. The pairing is a reasonable hypothesis that a lot of people in the longevity space find compelling. It is not a settled, proven combination with agreed human outcomes. What the research actually shows NMN is the more thoroughly researched of the pair in humans. Several clinical trials have looked at NMN supplementation and measured what happens to NAD+ levels and various markers. The evidence base is growing, though it's still early and trials are generally small and short. Resveratrol has a longer history of laboratory study but a more complicated human story. One persistent issue is absorption: resveratrol is poorly absorbed in the gut, and the small amount that does get into the bloodstream is broken down quickly. Independent laboratories have also reported difficulty replicating some of the earlier findings. None of that means resveratrol does nothing — it means the human evidence is less clear-cut than the enthusiasm around it sometimes suggests. So when you read that NMN and resveratrol "work better together," treat that as a hypothesis drawn mostly from preclinical research, not as an established fact about people. Why the pairing became so popular A lot of the visibility comes from one person. Professor David Sinclair, a researcher at Harvard whose lab studies NAD+ metabolism and the biology of ageing, has spoken publicly about taking NMN alongside resveratrol as part of his own personal routine. That's useful context, but worth holding lightly. A researcher's personal routine is not a clinical recommendation, and what one individual chooses to take tells you about their judgement, not about a tested protocol. How to think about it for yourself Do you want to keep things simple or experiment? Plenty of people take NMN on its own and are happy doing so. Starting with one variable makes it easier to know how you feel. If you do add resveratrol, absorption matters. Because plain resveratrol is poorly absorbed, the form and how it's taken are relevant. Some people take it with a source of fat to give the compound a better chance of getting into the body. Be realistic about timeframes and expectations. Neither compound is something you take once and notice. People who take them do so as a long-term, consistent habit — the same way they'd think about any part of a daily routine. Talk to a professional if you take medication or have a health condition. Resveratrol in particular can interact with some medicines. If you're on anything regular, or you're pregnant or breastfeeding, get individual advice before adding either compound. Where Ivvion fits Ivvion makes NMN — Essential at 500 mg a day and Elite, a 1,000 mg liposomal formulation built for absorption. We don't currently sell a resveratrol product, and we're not going to pretend the pairing is a finished, proven protocol in order to sell you more. If you choose to add resveratrol from another source, that's a reasonable thing to research — go in with clear eyes about what the evidence does and doesn't say. If you're new to NMN entirely, our complete guide to NMN in the UK is the better place to start. Food supplement. Not a medicine. Does not diagnose, treat, cure or prevent any disease. If you are pregnant, breastfeeding, on prescription medication, or have a health condition, consult your GP before taking any supplement.

The longevity shelf is crowded and getting more so. NMN, NR, resveratrol, spermidine, fisetin, CoQ10 — every few months a new molecule gets its moment. If you're trying to decide where to start, the marketing isn't much help, because nearly every product claims to be the one that matters most. So here's a level-headed comparison. The honest headline first: no single supplement has a proven longevity benefit in humans. What differs between these compounds is how much human research exists, how reliably they do the specific thing they're known for, and how early the science still is. That's the lens we'll use. One thing to get straight before the comparison These compounds aren't all trying to do the same job, so "which is best" is partly the wrong question. They cluster into different mechanisms that researchers study: NAD+ precursors — NMN and NR. Studied for their effect on NAD+ levels, a coenzyme that declines with age. Sirtuin-interacting compounds — resveratrol is the most well-known. Autophagy-related compounds — spermidine is most associated with this cellular "cleanup" process in research. Senolytics — fisetin, studied for its interaction with senescent ("worn-out") cells. Mitochondrial support — CoQ10, long studied in the context of cellular energy production. Knowing which bucket a compound sits in tells you more than any ranking. NMN NMN is a precursor to NAD+. Of the compounds on this list, it's one of the most actively studied in human trials — several clinical studies have measured its effect on NAD+ levels. The evidence base is still early: trials tend to be small and short, and raising a biomarker is not the same as a proven health outcome. But if you want a compound where the human research is comparatively active rather than purely preclinical, NMN is a reasonable place to look. NR (Nicotinamide Riboside) NR is the other main NAD+ precursor — a close cousin of NMN, different molecule, same destination. NR has its own body of human research and a longer commercial track record in some markets. The NMN-versus-NR debate is genuinely unsettled, and anyone who tells you one is definitively superior is ahead of the evidence. The short version: they're both NAD+ precursors, and the choice between them is closer than the marketing on either side admits. Resveratrol Resveratrol is the polyphenol most associated with sirtuins in laboratory research. Its weakness is absorption: plain resveratrol is poorly absorbed in the gut and broken down quickly, and independent labs have had trouble replicating some early findings. It's frequently paired with NMN, but the human evidence for resveratrol on its own is less clear-cut than its fame suggests. Spermidine Spermidine is most associated with autophagy in research — the process by which cells clear out and recycle damaged components. The preclinical interest is real, and spermidine occurs naturally in foods like wheat germ, aged cheese and soy. As with the others, the human evidence is early. It's a different mechanism from the NAD+ story, which is exactly why some people are curious about it. Fisetin Fisetin is a plant compound studied as a senolytic — researched for whether it can help clear senescent cells, the worn-out cells that accumulate with age. Animal studies have been encouraging, and at least one small human study looked at markers of senescence. "Promising but early" is the fair summary. Fisetin is a watch-this-space compound rather than a settled one. CoQ10 CoQ10 is the most established of the group, with a long history of use in the context of cellular energy production. Natural levels are understood to decline with age. It sits in a different category from the NAD+ and senolytic compounds — less of a frontier molecule and more of a long-standing one. So where should you start? We're an NMN company, so take this with appropriate salt — but here's the reasoning we'd actually give a friend. Start with one compound, not five. Stacking everything at once means you'll never know what's doing what, and it's an expensive way to find out. Pick a single starting point and give it a fair, consistent run. Favour the compounds where human research is more active. Among this list, the NAD+ precursors — NMN and NR — have comparatively more human study behind the specific thing they're known for. That's a defensible reason to start there. Match the mechanism to your curiosity, not the hype. If the NAD+ story interests you, NMN or NR is the entry point. If you're drawn to autophagy or senolytic ideas, know that you're choosing a more experimental, earlier-stage area — and that's a legitimate choice as long as you go in clear-eyed. Keep your expectations honest. None of these is a shortcut, and none has a proven human longevity outcome. They're long-term, consistent habits for people who find the underlying science interesting — not switches that flip something on. Get individual advice if you take medication, are pregnant or breastfeeding, or have a health condition. Some of these compounds — resveratrol especially — can interact with medicines. Where Ivvion fits We make NMN: Essential at 500 mg a day, and Elite, a 1,000 mg liposomal formulation built for absorption. We chose NMN because it's one of the more actively studied compounds in this space, and we chose liposomal for Elite because absorption is the real bottleneck for a lot of supplements. We're not going to tell you NMN beats every alternative, because the evidence doesn't support a clean league table. What we can say is that it's a reasonable, well-studied place to start. Food supplement. Not a medicine. Does not diagnose, treat, cure or prevent any disease. If you are pregnant, breastfeeding, on prescription medication, or have a health condition, consult your GP before taking any supplement.

If you're a woman in your forties or fifties and you've started reading about NMN, you've probably noticed two things. The marketing is loud. And almost none of it is written for you. Most NMN content was written by, and for, men over 50 in California. That doesn't mean the supplement is only relevant to them — it means the conversation has skipped a question worth asking honestly: what is the research actually studying, and what would a careful woman over 40 want to know before buying? This is that article. We sell NMN, so we have an interest in your buying it. We've still tried to write the piece we'd want our sister or our mother to read first. What NMN is (the boring, accurate version) NMN — nicotinamide mononucleotide — is a small molecule the body uses as a precursor to NAD+. NAD+ is a coenzyme that sits in the middle of how your cells produce energy and repair themselves. The reason NMN became a research subject is straightforward: NAD+ levels in human tissue decline with age. The decline is gradual, it varies between individuals, and the curve is steeper from roughly the late thirties onward. That biology is well-documented. What is not yet established at the standard of evidence required for medicinal claims is whether topping NAD+ back up via NMN supplementation reverses, slows, or affects specific outcomes in women over 40. That distinction matters. We will not tell you NMN will "balance your hormones" or "ease your menopause" or "give you energy". Those claims are not permitted for a food supplement in the UK, and the human research is not yet at a level where they would be honest. What we can tell you is this: NAD+ biology is real, the decline with age is real, and the research being done is serious. The studies are getting bigger and more rigorous each year. That's why a calm, well-formulated NMN supplement has become a normal part of many over-40 wellness routines. Why women over 40 are asking different questions Women's physiology in the perimenopausal and post-menopausal window is different in ways the supplement industry mostly ignores. Metabolic rate shifts. Body composition changes through this window. Many women become more interested in supplements that support general cellular health rather than acute, stimulant-style effects. Bone, joint and skin biology all undergo changes that women notice before the calendar says "menopause". The supplement industry frequently overpromises here. We won't. Drug interactions. Many women over 40 are taking other things — HRT, statins, thyroid medication, antidepressants. NMN's safety profile in healthy adults is encouraging in the studies done so far, but interactions with prescription medications have not been comprehensively studied. If you are on prescription medication, ask your GP before adding any supplement. We mean this — it's not a legal flourish. Cost-per-day matters more. Most women buying NMN over 40 are not biohackers. They want to know whether the supplement is worth the money over six or twelve months. That's a fair question and we answer it below. What the research is actually looking at Most human NMN trials to date are small (20–80 participants), short (8–24 weeks), and mixed-sex or male-only. The endpoints they measure include: NAD+ blood levels — does the supplement raise them? In most trials, yes, in a dose-dependent way. Physical function markers — walking pace, grip strength, treadmill performance. Mixed and modest results, sometimes in older subgroups. Sleep and recovery markers — some signals, methodologically variable. Safety and tolerability — consistently good at doses up to 1,000 mg/day. What you will not yet find: large, long-duration, female-specific trials with definitive outcomes. That's not a reason to avoid NMN. It's a reason to be honest about what you're buying — a credible precursor molecule with promising early research, not a guaranteed effect. We update this article quarterly as new research lands. (Last reviewed: May 2026.) How to choose an NMN supplement if you're a woman over 40 Purity. Look for a brand that publishes a third-party certificate of analysis (COA) for each batch. The COA should confirm NMN purity (≥99% is standard) and screen for heavy metals and microbial contaminants. If a brand doesn't publish a COA, treat that as the answer to your question. Dose. Most adult studies use between 250 mg and 1,000 mg per day. As a general structure: 500 mg/day is a sensible baseline. 1,000 mg/day is the higher end used in research and often chosen by people who want to start at the top of the studied range. Form. Powder-in-a-capsule NMN has historically had variable absorption. Liposomal formulations encapsulate the molecule in a phospholipid shell, which the research suggests improves bioavailability. Brand transparency. The supplement industry has a long history of opaque sourcing. The brands worth your money will tell you where the NMN is manufactured, how it's tested, and what's in the capsule besides the active ingredient. Cost-per-day, not cost-per-bottle. A £50 bottle that lasts 30 days is £1.67/day. A £75 bottle that lasts 60 days is £1.25/day. Work out the daily cost and decide whether it's a price you'd happily pay for the next six months. Subscribe & Save as a sanity check. A brand that offers a discounted subscription is usually signalling that it stands behind the product. Two practical scenarios Scenario 1 — "I'm 42, I exercise, I eat well, I'm curious." A reasonable place to start is 500 mg of a well-formulated NMN, taken in the morning, for three months. Pay attention to sleep, recovery and general energy. Track loosely — don't obsess. After three months, you'll have enough sense of whether you want to continue. Scenario 2 — "I'm 51, I'm post-menopausal, I'm careful with what I take." Talk to your GP if you're on any prescription medication. If you're cleared and you want to try NMN, start at 500 mg/day and reassess at three months. You can step up to 1,000 mg if you'd like to. In both cases: it is a food supplement, not a medicine, and it is part of a healthy lifestyle — not a substitute for one. Where Ivvion fits We make two NMN supplements: Essential — 500 mg/day, capsule form, third-party tested, manufactured in the UK. Elite — 1,000 mg/day, liposomal formulation for higher absorption, third-party tested, manufactured in the UK. We also run a 3-minute quiz that asks five honest questions and recommends one of them. If you'd rather read more first, our NMN UK pillar guide covers the science in more depth. A note on what we won't say We will not tell you NMN will give you more energy. We will not tell you it will ease menopause symptoms. We will not tell you it will improve sleep or focus or skin or any other outcome you might be hoping for. UK advertising rules forbid these claims for food supplements, and on top of the rules, we think you'd rather we be straight with you than sell you a feeling. What we will say is: the underlying biology is real, the research is moving in interesting directions, and a well-made NMN is — for a lot of women over 40 — a sensible addition to a routine you've already built. That's the whole pitch. Food supplement. Not a medicine. Does not diagnose, treat, cure or prevent any disease. If you are pregnant, breastfeeding, on prescription medication, or have a medical condition, consult your GP before taking any supplement.